In addition to One Disease, Sam has established a number of other organisations. He is the founder of Zambrero, Mexican with a mission: a healthy quick-service restaurant franchise as well as humanitarian enterprise committed to tackling world hunger; Mejico, a modern market-fresh Mexican restaurant & tequila bar; INDU, a fresh, contemporary Indian restaurant with a focus on the fragrant food of coastal India, and Florey, a revolusionary healthcare service, bringing together health advocacy, a comfortable space, technology and education to improve the experience of visiting a general practice.